ProPath, a Sonic Healthcare anatomic pathology practice, is privileged to include Craig E. Litz, M.D., as a part of its dynamic medical staff. Dr. Litz is an award-winning, double board-certified pathologist with robust professional experience and a substantial publication history. He was named a 2020 Best Doctor by D Magazine.

Dr. Litz graduated with a Bachelor of Science degree in chemistry from Georgetown University in Washington, D.C. He earned his medical degree from the Medical College of Virginia in Richmond. During medical school, he was also a summer research assistant at the Naval Research Laboratories in Washington, D.C. He served a residency in anatomic and clinical pathology at the University of Minnesota in Minneapolis, where he served as chief resident. During his residency, he held a postdoctoral research position in the Department of Laboratory Medicine and Pathology at the University of Minnesota. He completed a fellowship in hematopathology, also at the University of Minnesota.

Dr. Litz has extensive professional experience, including teaching appointments and several medical directorships. He started his professional practice as a pathologist in the Department of Laboratory of the University of Minnesota Medical School in Minneapolis. While there, he held a teaching appointment in the hematopathology division of the same department, starting as an instructor before moving up to assistant, then associate, professor. He also held a position as an associate member of the graduate faculty in clinical laboratory science at the University of Minnesota. He then spent a year as a pathologist in the pathology department of Fairview Riverside Medical Center in Minneapolis. Dr. Litz has been a member of the ProPath team since 1997, starting as a pathologist. During this time, he served as the vice-chief, and then chief, of medical staff at St. Paul University Hospital in Dallas, TX, and currently holds the position of clinical professor in the pathology department of the University of Texas Southwestern Medical Center. Dr. Litz has held several directorships. He was the director of hematology laboratory at St. Paul University Hospital. He was also the medical director of Texas Health Surgery Center Dallas and the PPS medical director of North Central Surgical Center. He is currently the medical director of Texas Scottish Rite Hospital for Children and the North Center Surgical Center, both in Dallas. Dr. Litz is ProPath’s director of hematopathology division.

Dr. Litz has a considerable list of publications. He has a notable collection of peer reviewed publications in medical journals such as the American Journal of Surgery, American Journal of Clinical Pathology, Journal of Surgical Pathology, and Human Pathology, among others. He has written multiple book chapters, one in Anderson’s Pathology, 10th ed., and the other in Neoplastic Hematopathology. Dr. Litz has also presented and published an extensive list of abstracts and given a number of invited talks.

Dr. Litz belongs to multiple professional organizations, including the American Society of Clinical Oncology, American Society for Clinical Pathology, and American Society of Hematology, among others. He is a fellow of the College of American Pathologists.

Dr. Litz holds full medical licensure and is board certified in hematology and anatomic and clinical pathology by the American Board of Pathology.

Education

Georgetown University (BS)
Washington, D.C.

Medical College of Virginia (MD)
Richmond, VA

Postgraduate Training

Hematopathology Fellowship
University of Minnesota
Minneapolis, MN

Anatomic and Clinical Pathology Residency
(Chief Resident)
University of Minnesota
Minneapolis, MN

Professional Memberships

College of American Pathologists, Fellow
American Gastroenterological Association
American Medical Association
American Society of Clinical Oncology
American Society for Clinical Pathology
American Society of Hematology
Dallas County Medical Society
Society for Hematopathology
Texas Society of Pathologists
United States and Canadian Academy
of Pathology

Peer-Reviewed Articles

1. Litz CE, Cavagnolo RZ. Polymerase chain reaction in the diagnosis of onychomycosis: a large, single-institute study. Br J Dermatol. 2010;163(3):511-514.
   
   
2. Litz CE, Beitsch PD, Roberts CA, Ewing G, Clifford E. Intraoperative cytologic diagnosis of breast sentinel lymph nodes in the routine, nonacademic setting: A highly specific test with limited sensitivity. Breast J. 2004;10(5):383-387.
   
   
3. Roberts CA, Beitsch PD, Litz CE, et al. Interpretive disparity among pathologists in breast sentinel lymph node evaluation. Am J Surg. 2003;186(4):324-329.
   
   
4. Nemunaitis J, Cunningham C, Senzer N, Kuhn J, Cramm J, Litz CE, Cavagnolo R, Cahill A, Clairmont C, Sznol M. Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients. Cancer Gene Ther. 2003;10(10):737-744.
   
   
5. Fine BA, Munoz AK, Litz CE, Gershenson DM. Primary medical management of recurrent aggressive angiomyxoma of the vulva with a gonadotropin-releasing hormone agonist. Gynecol Oncol. 2001;81:120-122.
   
   
6. Litz CE, Hanson M. A new form of T-cell PTLD. Am J Clin Pathol. 2000;113(4):598.
   
   
7. Froberg M, Brunning R, Dorion P, Litz C, Torlakovic E. Demonstration of clonality in neutrophils using FISH in a case of chronic neutrophilic leukemia. Leukemia. 1998;12(4):623-626.
   
   
8. Litz C, Etzell J. Aberrant DNA methylation of genomic regions translocated in myeloid malignancies. Leuk Lymphoma. 1998;30(1-2):1-9.
   
   
9. Stroncek D, Shankar R, Litz C, Clement L. The expression of the NB1 antigen on myeloid precursors and neutrophils from children and umbilical cords. Transfus Med. 1998;8(2):119-123.
   
   
10. Kappel TJ, Peterson CJ, Litz CE. Clonal determination of carcinoid tumors of the appendix. J Surg Pathology. 1997;2:233-7.
    
    
11. Litz CE, Vos JA, Copenhaver CM. Aberrant methylation of the major breakpoint cluster region in chronic myeloid leukemia. Blood. 1996;88(6):2241-2249.
    
    
12. Hanson MN, Morrison VA, Peterson BA, Stieglbauer KT, Kubic VL, McCormick SR, McGlennen RC, Manivel JC, Brunning RD, Litz CE. Posttransplant T-cell lymphoproliferative disorders—an aggressive, late complication of solid-organ transplantation. Blood. 1996;88(9):3626-3633.
    
    
13. Woronzoff-Dashkoff KK, Litz CE. Acute lymphoblastic leukemia in a case of essential thrombocythemia. Am J Clin Pathol. 1996;106(2):206-208.
    
    
14. Dusenbery KE, Steinbuch M, McGlave PB, Ramsay NKC, Blazar BR, Neglia JP, Litz CE, Kersey J, Woods WE. Autologous bone marrow transplantation in acute myeloid leukemia: the University of Minnesota experience. Int J Radiat Oncol Biol Phys. 1996;36(2):335-343.
    
    
15. Litz CE, Davies S, Brunning RD, Keuck B, Parkin JL, Gajl-Peczalska KJ, Arthur DC. Acute leukemia and the transient myeloproliferative disorder associated with Down’s syndrome: morphologic, immunophenotypic, and cytogenetic manifestations. Leukemia. 1995;9(9):1432-1439.
    
    
16. Torlakovic E, Hibbs JR, Miller JS, Litz CE. Intracellular bacteria in blood smears in patients with central venous catheters. Arch Intern Med. 1995;155(14):1547-1550.
    
    
17. Litz CE. The parental origin of the Philadelphia chromosome: evidence of additional, recurring recombinatorial events. Leukemia. 1995;9(4):734-45.
    
    
18. Schmitz LL, McClure JS, Litz CE, et al. Morphologic and quantitative changes in blood and marrow cells following growth factor therapy. Am J Clin Pathol. 1994;101(1):67-75.
    
    
19. Miller JS, Arthur DC, Litz CE, Neglia JP, Miller WJ, Weisdorf DJ. Myelodysplastic syndrome after autologous bone marrow transplantation: an additional late complication of curative cancer therapy. Blood. 1994;83(12):3780-3786.
    
    
20. Coad JE, Arthur DC, Gajl-Peczalska KJ, Litz CE. Late developing Philadelphia chromosomes in a case of T-cell acute lymphoblastic leukemia. Leukemia. 1994;8:889-94.
    
    
21. Litz C, Copenhaver C. Paternal origin of the rearranged major breakpoint cluster region in chronic myeloid leukemia. Blood. 1994;83(12):3445-3448.
    
    
22. Nguyen PL, Arthur DC, Litz CE, Brunning RD. Fluorescent in situ hybridization (FISH) detects trisomy 8 in myeloid cells in chronic myelogenous leukemia (CML): a study of archival blood and bone marrow smears. Leukemia. 1994; 8:1654-62.
    
    
23. Torlakovic E, Litz CE, McClure JS, Brunning RD. Direct detection of the Philadelphia chromosome in CD20-positive lymphocytes in chronic myeloid leukemia by tri-color immunophenotyping/FISH. Leukemia. 1994; 8(11):1940-3.
    
    
24. Lee S, McGlennen R, Litz C. Clonal determination by the fragile X (FMRI) and phosphoglycerage kinase (PGK) genes in hematologic malignancies. Cancer Res. 1994;54:5212-5216.
    
    
25. Schmitz LL, Litz CE, Brunning RD. Morphologic and quantitative alterations in hematopoietic cells associated with growth factor therapy: review of the literature. Hematol Pathol. 1994; 8(3):55-73.
    
    
26. McClure JS, Litz CE. Chronic myelogenous leukemia: molecular diagnostic considerations. Hum Pathol. 1994;25(6):594-597.
    
    
27. Litz CE, McClure JS, Copenhaver CM, Brunning RD. Duplication of small segments within the major breakpoint cluster region in chronic myelogenous leukemia. Blood. 1993;81(6):1567-1572.
    
    
28. Goldfarb AN, Litz CE. A novel approach to clonality analysis. Alternations in genomic methylation of Epstein-Barr virus transformed lymphocytes. Pathol Res Pract. 1993; 189(3):312-315.
    
    
29. Litz CE, Brunning RD. Chronic lymphoproliferative disorders: classification and diagnosis. Baillieres Clin. Haematol. 1993;6:767-783.
    
    
30. Litz CE. Case of the quarter. Society of Hematopathology. 1993 November.
    
    
31. Litz CE, McClure JS, Coad JE, Goldfarb AN, Brunning RD. Methylation status of the major breakpoint cluster region in Philadelphia chromosome negative leukemias. Leukemia. 1992;6:35-41.
    
    
32. Coad J, Lander T, Litz C. Inhibition of restriction endonucleases by common clinical anticoagulants. Anal Biochem. 1992;205(2):368-369.
    
    
33. Singleton TP, Gloria A, Gu F, Litz CE, Hagen K, Kiang DT, Strickler JG. Detection of c-erbB-2 activation in paraffin- embedded tissue by immunohistochemistry. Hum Pathol. 1992;23(10):1141-1150.
    
    
34. d’Amore ESG, Manivel JC, Gajl-Peczalska KJ, Litz CE, Copenhaver CM, Shapiro RS, Strickler JG. B-cell lymphoproliferative disorders after bone marrow transplant: an analysis of ten cases with emphasis on epstein-barr virus detection by in situ hybridization. Cancer. 1991;68(6):1285-1295.
    
    
35. Litz CE, Arthur DC, Rausch D, Copenhaver CM, Coad JE, Brunning RD. Transformation of chronic lymphocytic leukemia to a small non-cleaved cell lymphoma: a cytogenetic, immunological and molecular study. Leukemia. 1991;5(11):972-978.
    
    
36. McClure JS, Litz CE. PCR detection of a Maell polymorphism in the human major breakpoint cluster region (BCR). Nucleic Acids Res. 1991;19(18):5090.
    
    
37. Litz CE, Goldfarb AN, Strickler JG, Brunning RD. Presence of cell lineage-specific hypomethylated sites in the major breakpoint cluster region (BCR). Cancer Res. 1990;50(16):4984-4990.
    
    
38. Litz CE, Swaim W, Dalmasso A. Factor XI deficiency: genetic and clinical studies of a single kindred. Am J Hematol. 1988;28(1):8-12.
    
    
39. Litz CE, Taylor K, Qiu JS, Pescovitz OH, de Martinville B. Absence of detectable chromosomal and molecular abnormalities in monozygotic twins discordant for the Wiedemann-Beckwith syndrome. Am J Med Genet. 1988;30:821-33.
    
    

Book Chapters

1. Litz CE, McClure JS, Brunning RD. Blood and bone marrow pathology. In: Damjanov I, Linder J, eds. Anderson’s Pathology. 10^th  ed. St. Louis, MO: Mosby; 1996.
   
   
2. Litz CE, Brunning RD. Acute myeloid leukemias. In: Knowles D, ed. Neoplastic Hematopathology. Baltimore, MD: Williams & Wilkins; 1992.
   
   

Book Reviews

1. Litz CE, Brunning RD, reviewers. Modern Pathology. 1991. Review of: Desseroth AB, Arlinghaus RB, eds. Chronic Myelogenous Leukemia: Molecular Approaches to Research and Therapy. New York, NY: Decker; 1991.
   
   

Personal Communications

1. Schmitz LL, McClure JS, Copenhaver C, Litz CE. PCR-based sequence detection of an EagI polymorphism in the human major breakpoint cluster region (M-bcr). Genome Data Base, 1992.
   
   
2. McClure JS, Schmitz LL, Copenhaver C, Litz CE. PCR-based sequence detection of a DpnII polymorphism in the human major breakpoint cluster region (M-bcr). Genome Data Base, 1992.
   
   

Abstracts

1. Roberts CA, Beitsch PD, Litz CE, Ewing GE, Hilton DS, Clifford E, Taylor W, Hapke MR, Babaian A, Khalid I, Hall J, Lindberg G, Molberg K, Saboorian H. Pathologists interpretative disparity in breast sentinel lymph nodes [pdb]. American Society of Breast Surgeons Meeting, Atlanta, GA, 2003.
   
   
2. Litz CE, Beitsch PD, Clifford E, Roberts CA, Ewing, G. Intraoperative axillary sentinel lymph node touch imprints lack sensitivity in detecting metastatic breast carcinoma. 24th Annual San Antonio Breast Cancer Symposium, San Antonio, TX, 2001.
   
   
3. Litz C, Miller RT, Ewing G, Odell D, Clifford E, Beitsch P. Intraoperative sentinel lymph node touch imprints are not sensitive in detecting metastatic carcinoma. Mod Pathol. 2000;13(1):26A.
   
   
4. Beitsch P, Clifford E, Litz CE, Ewing GE. Prospective treatment of DCIS with sentinel lymph node biopsy. Sentinel Node.
   
   
5. Etzell J, Litz CE. Aberrant methylation of the RARA gene in acute promyelocytic leukemia. Blood. 1999.
   
   
6. Hanson MN, Litz CE, Stieglbauer KT, McCormick SR, Brunning RD. Aggressive T-cell lymphomas of the bone marrow and blood. Mod Pathol. 1996;9:113A.
   
   
7. Dusenbery KE, Steinbuch M, Litz CE, McGlave PB, Ramsay NKC, Blazar BR, Neglia JP, Kersey JH, Woods WG. Autologous bone marrow transplantation for acute myeloid leukemia beyond first remission. Am Rad Soc. 1995.
   
   
8. Litz CE, Brunning RD, Peterson BA, Key NS, Morrison VA. Lymphoproliferative disorders of T-cell origin in solid organ transplant recipients. Blood. 1995;86:340a.
   
   
9. Litz CE, Copenhaver CM. Aberrant hypermethylation of the major breakpoint cluster region (M-bcr) in Philadelphia chromosome (Ph) negative cells of patients with Ph positive chronic myeloid leukemia (CML). Blood.
   1995;86:734a.
   
   
10. Prosper F, Miller JS, McGlennen RC, Litz CE, Key NS. Rearrangement of the beta chain of the T-cell receptor in natural killer cell lymphoma. Blood. 1995;86:721a.
    
    
11. Litz CE, Stieglbauer KT, Hanson MN, Copenhaver CM. Aberrant hypermethylation of the major breakpoint cluster region in Philadelphia chromosome (Ph) positive chronic myeloid leukemia (CML). Am J Hum Genet. 1995;57:A71.
    
    
12. Stieglbauer KT, Litz CE, McGlennen RC, Hanson MN, Arthur DC, Brunning RD. Detection of the Philadelphia chromosome (Ph) by interphase fluorescence in-situ hybridization (FISH) in bone marrow transplant (BMT) patients (pts) with chronic myeloid leukemia (CML): a comparative analysis with molecular and cytogenetic (CYTO) techniques. Mod Pathol. 1995.
    
    
13. Peterson CJ, Kappel TJ, Litz CE. Clonal determination of appendiceal carcinoids. Mod Pathol. 1995.
    
    
14. Lee ST, McClure JS, Brunning RD, Litz CE. Utility of a polymerase chain reaction (PCR) technique for clonal analysis. Mod Pathol. 1994;7:164A.
    
    
15. Schmitz LL, McClure JS, Litz CE, Dayton V, Weisdorf DJ, Parkin JL, Brunning RD. Morphologic and quantitative changes in blood and marrow cells following growth factor therapy. Mod Pathol. 1993;6:574A.
    
    
16. McClure JS, McGlennen RC, Brunning RD, Copenhaver CM, Parkin JL, Litz CE. The polymerase chain reaction (PCR) as a screening test in the diagnosis of chronic myelogenous leukemia (CML). Mod Pathol. 1993;6:551A.
    
    
17. Litz CE, Davies S, Brunning RD. Morphologic and biologic features of the transient myeloproliferative syndrome in Down’s syndrome. Mod Pathol. 1993;6:545A.
    
    
18. Killeen AA, Lewis CM, Moyer Y, Staggs RA, Litz CE, McClure JS, McGlennen RC. Identification and quantification of BCR-abl transcripts in bone marrow by reverse transcriptase PCR and high performance liquid chromatography. Am J Hum Genet. 1993;53:314A.
    
    
19. Litz CE, Copenhaver CM. Paternal origin of the M-bcr in chronic myelogenous leukemia. Am J Hum Genet. 1993;53:326A.
    
    
20. Miller JS, Arthur DC, Litz CE, Neglia JP, Miller WJ, Weisdorf DJ. Myelodysplastic syndrome following autologous bone marrow transplantation: an additional late complication of curative cancer therapy. Blood. 1993;82:455A.
    
    
21. Nguyen PL, Arthur DC, Litz CE, Brunning RD. Fluorescent in situ hybridization (FISH) detects trisomy 8 in myeloid cells in chronic myeloid leukemia (CML): a study of archival blood and bone marrow smears. Blood. 1993;82:530A.
    
    
22. Litz CE, McClure JS, Copenhaver CM, Brunning RD. Partial duplication of the major breakpoint cluster region in chronic myelogenous leukemia. Blood. 1992;80:786A.
    
    
23. Litz CE, Goldfarb AN, Strickler JG, Brunning RD. A novel DNA marker of myeloid differentiation. Mod Pathol. 1990;3:338A.
    
    
24. Litz CE, Coad JE, Goldfarb AN, Brunning RD. M-bcr methylation patterns are cell lineage specific and maturationally related in hematopoiesis.  Blood. 1990;76:402A.
    
    
25. Litz CE, Coad JE, Cohenhaver C, Brunning RD. Aberrant methylation patterns of the rearranged major breakpoint cluster region (M-bcr) in chronic myelogenous leukemia (CML) are associated with breakpoint location. Blood. 1990;76:941A.
    
    
26. Litz CE, Goldfard AN, Strickler JG, Brunning RD. Hypomethylated sites in the major breakpoint cluster region (M-bcr) of chromosome 22 are cell lineage specific and correlate with chronic myelogenous leukemia (CML) breakpoints. Blood. 1989;74:321A.
    
    
27. Litz CE, Taylor K, Qiu JS, Pescovitz OH, de Martinville B. Absence of detectable chromosomal and molecular abnormalities in monozygotic twins discordant for the Wiedermann-Beckwith syndrome. Aca Clin Lab Phy Sci. 1988.
    
    
28. Litz CE, Snover D. An immunohistochemical classification of appendiceal carcinoids. Lab Invest. 1987;56:A44.
    
    
29. Sheinson RS, Litz CE. Hydrogen peroxide concentrations in spontaneous ignition. Abs Pap ACS 1982;183:14.